Varicella Zoster Virus (VZV) IgG, Immunity Status

TEST: 096010
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CPT: To be determined. Updates will be made when available. 
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Synonyms

Chickenpox

Specimen Requirements

Specimen

Serum

Volume

0.5 mL

Minimum Volume

0.2 mL

Container

Red-top tube or gel-barrier tube

Collection

If a tube other than a gel-barrier tube is used, transfer separated serum to a plastic transport tube. Do not freeze gel-barrier tube (pour off serum first).

Storage Instructions

Room temperature

Stability Requirements

TemperaturePeriod
Room temperature14 days
Refrigerated14 days
Frozen14 days
Freeze/thaw cyclesStable x4

Causes for Rejection

Hemolysis; lipemia; gross bacterial contamination

Test Details

Use

This test is used to determine the immune status of individuals to the varicella zoster virus (VZV) and offer documentation of previous infection with VZV in an individual without a documented history of completion of the VZV vaccination series.

Limitations

Routine testing for varicella immunity following vaccination is unnecessary because commercially available VZV IgG assays are not sensitive enough to detect all seroconversions after a vaccination.

Methodology

Chemiluminescent immunoassay (CLIA)

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The LOINC® codes are copyright © 1994-2021, Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. Permission is granted in perpetuity, without payment of license fees or royalties, to use, copy, or distribute the LOINC® codes for any commercial or non-commercial purpose, subject to the terms under the license agreement found at https://loinc.org/license/. Additional information regarding LOINC® codes can be found at LOINC.org, including the LOINC Manual, which can be downloaded at LOINC.org/downloads/files/LOINCManual.pdf